Article
Loss-of-function polymorphic variants of the human angiotensin II type 1 receptor.
Molecular pharmacology - 1 Mar 2004
Hansen Jakob Lerche, Haunsø Stig, Brann Mark R, Sheikh Søren P, Weiner David M
Abstract excerpt
The angiotensin II type 1 (AT1) receptor is the primary effector for angiotensin II (Ang II), a key peptide regulator of blood pressure and fluid homeostasis. AT1 receptors are involved in the pathogenesis of several cardiovascular diseases, including hypertension, cardiac hypertrophy, and conges...
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