Article
Divergent evolution of hepatitis C virus in liver and peripheral blood mononuclear cells of infected patients.
Journal of medical virology - 1 Jan 1999
Maggi F, Fornai C, Morrica A, Vatteroni M L, Giorgi M, Marchi S, Ciccorossi P, Bendinelli M, Pistello M
Abstract excerpt
In infected individuals, hepatitis C virus (HCV) exists as a variably complex population of related genetic variants known as quasispecies. The quasispecies of HCV were studied previously in 10 chronically infected patients by single-strand conformation polymorphism analysis of a segment of the e...
Topics
- Cells, Cultured
- Evolution, Molecular
- Genetic Variation
- Hepacivirus
- Hepatitis C, Chronic
- Humans
- Leukocytes, Mononuclear
- Liver
- Liver Cirrhosis
- Phylogeny
- Polymerase Chain Reaction
- RNA, Viral
