Article
Genetic determination of plasma aldosterone levels in essential hypertension.
American journal of hypertension - 1 Jul 1998
Pojoga L, Gautier S, Blanc H, Guyene T T, Poirier O, Cambien F, Benetos A
Abstract excerpt
The renin-angiotensin-aldosterone system plays an important role in large artery structure and blood pressure homeostasis. Among the genes coding for different components of this system, the aldosterone synthase (CYP11B2) gene could play an important role, but has been less investigated. We examined the role of two variations of the aldosterone synthase gene (CYP11B2), one located in the promoter of the gene,...
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