Article
Genetic control of the circulating concentration of transforming growth factor type beta1.
Human molecular genetics - 1 Jan 1999
Grainger D J, Heathcote K, Chiano M, Snieder H, Kemp P R, Metcalfe J C, Carter N D, Spector T D
Abstract excerpt
The concentration of transforming growth factor beta (TGF-beta) in plasma has been correlated with the development of several diseases, including atherosclerosis and certain forms of cancer. However, the mechanisms that control the concentration of TGF-beta in plasma are poorly understood. In a s...
Topics
- Adult
- Aged
- Alleles
- Arteriosclerosis
- Base Sequence
- Bone Diseases
- DNA
- DNA Primers
- Female
- Genetic Variation
- Humans
- Linkage Disequilibrium
- Middle Aged
- Models, Genetic
- Neoplasms
- Polymorphism, Single-Stranded Conformational
- Promoter Regions, Genetic
- Transforming Growth Factor beta
