Article
Genetic control of the circulating concentration of transforming growth factor type beta1.
Human molecular genetics - 1 Jan 1999
Grainger D J, Heathcote K, Chiano M, Snieder H, Kemp P R, Metcalfe J C, Carter N D, Spector T D
Abstract excerpt
The concentration of transforming growth factor beta (TGF-beta) in plasma has been correlated with the development of several diseases, including atherosclerosis and certain forms of cancer. However, the mechanisms that control the concentration of TGF-beta in plasma are poorly understood. In a study of 170 pairs of female twins (average age 57.7 years) we show that the concentration of active plus...
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