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TGFB1 +869 T > C (rs1800470) variant is independently associated with susceptibility, laboratory activity, and TGF-β1 in patients with systemic lupus erythematosus.

Autoimmunity - 1 Dec 2021

Stadtlober Nicole Perugini, Flauzino Tamires, Santos Lorena Flor da Rosa Franchi, Iriyoda Tatiana Mayumi Veiga, Costa Neide Tomimura, Lozovoy Marcell Alysson Batisti, Reiche Edna Maria Vissoci, Simão Andréa Name Colado

Abstract excerpt

The aim of this study was to evaluate the association of the +869 T > C (rs1800470) and -509 C > T (rs1800469) TGFB1 variants, individually or in haplotypes structure, with susceptibility, autoantibodies, disease activity, and TGF-β1 plasma levels in patients with systemic lupus erythematosus (SLE). The study included 203 patients with SLE and 165 healthy controls. TGFB1 variants were determined by real-time...

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PMID: 34519592
DOI: 10.1080/08916934.2021.1975680

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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