Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thyroid hormone regulation of rat hepatocyte proliferation and polyploidization

1 Jan 1999

Abstract excerpt

The liver of adult mammals contains various classes of polyploid hepatocytes produced by a process that is partially regulated by hormones. However, it is not well understood how the hormones affect the rate of hepatocyte proliferation under physiological conditions. Here we have studied the specific roles of 3,5,3'-triiodothyronine (T3), growth hormone (GH), and sex steroids on the percentage of diploid nuclei...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Growth Hormone and Insulin-like Growth Factors
Share to Liver physiology and pathology
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9886991
DOI: 10.1152/ajpgi.1999.276.1.g155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thyroid hormone regulation of rat hepatocyte proliferation and polyploidizationPMID 9886991Read ↗

Hepatocytes Polyploidization and Cell Cycle Control in Liver PhysiopathologySemantic proximity Read ↗

Hepatocyte polyploidization and its association with pathophysiological processesSemantic proximity Read ↗

Differential Roles for Diploid and Polyploid Hepatocytes in Acute and Chronic Liver InjurySemantic proximity Read ↗

Polyploidy and liver proliferation: Central role of insulin signalingSemantic proximity Read ↗

Polyploidization of Hepatocytes: Insights into the Pathogenesis of Liver DiseasesSemantic proximity Read ↗

Implications of Polyploidy and Ploidy Alterations in Hepatocytes in Liver Injuries and CancersSemantic proximity Read ↗

Liver Cell Polyploidization: A Pivotal Role for Binuclear HepatocytesSemantic proximity Read ↗

Sexually Dimorphic Regulation of Gonadotrope Cell Hyperplasia in Medaka Pituitary via Mitosis and TransdifferentiationSemantic proximity Read ↗

The Fischer rat thyroid cell line FRTL-5 exhibits a nondiploid karyotype.Semantic proximity Read ↗

Relationship of hepatocyte ploidy levels with body size and growth rate in mammalsSemantic proximity Read ↗

Gender-specific changes in thyroid hormone-glucuronidating enzymes in rat liver during short-term fasting and long-term food restriction.Semantic proximity Read ↗

Carcinogenic effect of N-nitrosodimethylamine on diploid and triploid zebrafish (Danio rerio).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.