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Polyploidization of Hepatocytes: Insights into the Pathogenesis of Liver Diseases

5 Jul 2022

Abstract excerpt

Polyploidization is a process by which cells are induced to possess more than two sets of chromosomes. Although polyploidization is not frequent in mammals, it is closely associated with development and differentiation of specific tissues and organs. The liver is one of the mammalian organs that displays ploidy dynamics in physiological homeostasis during its development. The ratio of polyploid hepatocytes...

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PMID: 35790893
DOI: 10.4062/biomolther.2022.070

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