Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Fischer rat thyroid cell line FRTL-5 exhibits a nondiploid karyotype.

Thyroid : official journal of the American Thyroid Association - 1 Jul 1998

Tasevski V, Benn D, Peters G, Luttrell B, Simpson A

Abstract excerpt

The FRTL-5 cell line is a stable thyroid cell line derived from the thyroid gland of the Fischer rat under defined culture conditions, which has been widely adopted as a model system for the study of thyroid cell function and for bioassay. While characterizing by flow cytometry FRTL-5 cells that were supplied to this laboratory by ATCC (American Type Cell Collection), we discovered that the cells (ATCC CRL8305)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Cyclic AMP
Share to Diploidy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Flow Cytometry

Share to Genotype

Share to Karyotyping

Source

Identifiers

PMID: 9709917
DOI: 10.1089/thy.1998.8.623

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Fischer rat thyroid cell line FRTL-5 exhibits a nondiploid karyotype.PMID 9709917Read ↗

Cytogenetic characterization of three human and three rat medullary thyroid carcinoma cell linesSemantic proximity Read ↗

Humanized medium (h7H) allows long-term primary follicular thyroid cultures from human normal thyroid, benign neoplasm, and cancer.Semantic proximity Read ↗

Long-term culture and functional characterization of follicular cells from adult normal human thyroids.Semantic proximity Read ↗

Contrasting effects of activating mutations of GalphaS and the thyrotropin receptor on proliferation and differentiation of thyroid follicular cells.Semantic proximity Read ↗

Oncogenic potential of a mutant human thyrotropin receptor expressed in FRTL-5 cells.Semantic proximity Read ↗

Dissociation of thyrotropin receptor function and thyrotropin dependency in rat thyroid tumour cell lines derived from FRTL-5.Semantic proximity Read ↗

PTH-C1: a rat continuous cell line expressing the parathyroid phenotype.Semantic proximity Read ↗

Thyroid hormone regulation of rat hepatocyte proliferation and polyploidizationSemantic proximity Read ↗

A spontaneously arising mutation in connexin32 with repeated passage of FRTL-5 cells coincides with increased growth rate and reduced thyroxine release.Semantic proximity Read ↗

Thyroid parafollicular cells. An accessible model for the study of serotonergic neurons.Semantic proximity Read ↗

The polarized epithelial phenotype is dominant in hybrids between polarized and unpolarized rat thyroid cell lines.Semantic proximity Read ↗

Immortalized human pituitary cells express glycoprotein alpha-subunit and thyrotropin beta (TSH beta).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.