Article
Early biochemical events in insulin-stimulated fluid phase endocytosis.
The American journal of physiology - 1 Jan 1999
Pitterle D M, Sperling R T, Myers M G, White M F, Blackshear P J
Abstract excerpt
We examined the initial molecular mechanisms by which cells nonselectively internalize extracellular solutes in response to insulin. Insulin-stimulated fluid phase endocytosis (FPE) was examined in responsive cells, and the roles of the insulin receptor, insulin receptor substrate-1 (IRS-1), phos...
Topics
- Adipose Tissue, Brown
- Androstadienes
- Animals
- Cell Line
- Endocytosis
- Enzyme Inhibitors
- Flavonoids
- Gene Expression
- Genes, Dominant
- Genes, ras
- Insulin
- Insulin Receptor Substrate Proteins
- Mice
- Mutation
- Phosphoproteins
- Receptor Protein-Tyrosine Kinases
- Receptor, Insulin
- Signal Transduction