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Article

Prolonged tyrosine kinase activation of insulin receptor by pY27-caveolin-2.

Biochemical and biophysical research communications - 1 Jan 2010

Kwon Hayeong, Pak Yunbae

Abstract excerpt

Caveolin-2 regulation of insulin receptor (IR) tyrosine kinase activity was investigated. An insulin time course revealed that rapidly induced tyrosine phosphorylation of IR was steadily maintained over a 180 min time period. In parallel, insulin-exerted IR interaction with caveolin-2 was detected as early as 5 min throughout until 180 min. Down-regulation of caveolin-2 by caveolin-2 siRNA arrested specifically a...

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Share to Enzyme Activation
Share to Insulin Receptor Substrate Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptor, Insulin

Share to RNA, Small Interfering

Share to STAT3 Transcription Factor

Share to Suppressor of Cytokine Signaling Proteins

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Source

Identifiers

PMID: 19895792
DOI: 10.1016/j.bbrc.2009.10.159

Genes

STAT3

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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