Article
B-raf and insulin synergistically prevent apoptosis and induce cell cycle progression in hematopoietic cells.
Cell cycle (Georgetown, Tex.) - 1 Feb 2004
Shelton John G, Chang Fumin, Lee John T, Franklin Richard A, Steelman Linda S, McCubrey James A
Abstract excerpt
FDC-P1 hematopoietic cells were conditionally transformed to grow in response to (delta)B Raf:ER, (delta)Raf-1:ER or DA-Raf:ER in which the hormone binding domain of the estrogen receptor (ER) was linked to the N-terminal truncated (delta) Raf genes. When these cells were deprived of IL-3 or beta...
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