Article
Gap junction expression following UVC-induced neoplastic transformation in human hybrid cell lines.
Carcinogenesis - 1 Dec 1998
Ehring G R, Antoniono R J, Redpath J L
Abstract excerpt
Decreased connexin gene expression and loss of the capacity for either homologous or heterologous intercellular communication has been associated with neoplastic transformation. We tested the hypothesis that loss of gap junctional intercellular communication (GJIC) correlates with tumorigenic potential in the HeLa x skin fibroblast human hybrid cell system. Connexin gene expression, gap junction function and...
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