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Article

Connexins as targets for cancer chemoprevention and chemotherapy.

Biochimica et biophysica acta - 20 Dec 2005

King Timothy J, Bertram John S

Abstract excerpt

Cells within a tissue continuously interact to coordinate normal tissue functions and maintain homeostasis. Gap junctional communication (GJC), mediated by the connexin protein family, allows this type of intercellular crosstalk resulting in synchronized and cooperative tissue behavior such as cardiac contraction. In cancer, loss of these types of cell:cell interactions has been shown to facilitate tumorigenesis...

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Identifiers

PMID: 16263076
DOI: 10.1016/j.bbamem.2005.08.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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