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Article

Role of connexin (gap junction) genes in cell growth control: approach with site-directed mutagenesis and dominant-negative effects.

Toxicology letters - 1 Aug 1998

Omori Y, Duflot-Dancer A, Mesnil M, Yamasaki H

Abstract excerpt

Evidence is accumulating that connexin (Cx) genes form a family of tumor-suppressor genes. Our long-standing study revealed that, in almost all tumors, some abnormality in gap junction is observed, including loss or reduction of expression, aberrant localization of gap junction. In this study, we have examined the dominant-negative effects of mutant (prepared by site-directed mutagenesis) Cx43 constructs in C6...

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Source

Identifiers

PMID: 9820654
DOI: 10.1016/s0378-4274(98)00056-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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