Article
Reversion of UVC-induced tumorigenic human hybrid cells to the non-tumorigenic phenotype.
European journal of cancer (Oxford, England : 1990) - 1 Feb 1996
Sun C, Antonionio R J, Redpath J L
Abstract excerpt
Non-tumorigenic HeLa x skin fibroblast human hybrid cells were UVC-irradiated (10 J/m2) and induced to neoplastic transformation with accompanying morphological change and expression of the HeLa tumour-associated antigen, intestinal alkaline phosphatase (IAP). A single-cell-derived cell line was cloned out of a neoplastically transformed focus and designated as UV-12. In low density culture, this cell line...
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