Reversion of UVC-induced tumorigenic human hybrid cells to the non-tumorigenic phenotype.

doi:10.1016/0959-8049(95)00581-1

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Article

Reversion of UVC-induced tumorigenic human hybrid cells to the non-tumorigenic phenotype.

European journal of cancer (Oxford, England : 1990) - 1 Feb 1996

Sun C, Antonionio R J, Redpath J L

Abstract excerpt

Non-tumorigenic HeLa x skin fibroblast human hybrid cells were UVC-irradiated (10 J/m2) and induced to neoplastic transformation with accompanying morphological change and expression of the HeLa tumour-associated antigen, intestinal alkaline phosphatase (IAP). A single-cell-derived cell line was...

Topics

Alkaline Phosphatase
Cell Division
Cell Transformation, Neoplastic
Fibroblasts
HeLa Cells
Humans
Hybrid Cells
Kinetics
Models, Biological
Phenotype
Ultraviolet Rays

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