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Article

New alleles of the platelet glycoprotein Ibalpha gene.

British journal of haematology - 1 Dec 1998

Corral J, González-Conejero R, Lozano M L, Rivera J, Vicente V

Abstract excerpt

Platelet membrane glycoprotein Ibalpha (GP Ibalpha) bears two molecular polymorphisms which are in linkage disequilibrium: the C/T dimorphism at codon 145 (HPA-2) and the variable number of tandem repeats (VNTR) polymorphism in the macroglycopeptide region. The frequencies of these two polymorphi...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Female
Gene Frequency
Genetic Linkage
Genotype
Humans
Male
Middle Aged
Pedigree
Platelet Glycoprotein GPIIb-IIIa Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Genetic

Source

Identifiers

PMID: 9886311
DOI: 10.1046/j.1365-2141.1998.01117.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9886311-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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New alleles of the platelet glycoprotein Ibalpha gene.PMID 9886311Read ↗

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The largest isoform of platelet membrane glycoprotein Ib alpha is commonly distributed in eastern Asian populations.Semantic proximity Read ↗

Frequency and functional relevance of genetic threonine145/methionine145 dimorphism in platelet glycoprotein Ib alpha in an Italian population.Semantic proximity Read ↗

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The largest variant of platelet glycoprotein Ib alpha has four tandem repeats of 13 amino acids in the macroglycopeptide region and a genetic linkage with methionine145.Semantic proximity Read ↗

Genetic and structural characterization of an amino acid dimorphism in glycoprotein Ib alpha involved in platelet transfusion refractoriness.Semantic proximity Read ↗

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Polymorphism of human glycoprotein Ib alpha results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region. Structure/function implications.Semantic proximity Read ↗

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