Frequency and functional relevance of genetic threonine145/methionine145 dimorphism in platelet glycoprotein Ib alpha in an Italian population.

doi:10.1046/j.1537-2995.1996.361097017175.x

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Article

Frequency and functional relevance of genetic threonine145/methionine145 dimorphism in platelet glycoprotein Ib alpha in an Italian population.

Transfusion - 1 Oct 1996

Mazzucato M, Pradella P, de Angelis V, Steffan A, de Marco L

Abstract excerpt

BACKGROUND: Threonine145/methionine145 dimorphism in platelet glycoprotein (GP) Ib alpha defines the human platelet antigen (HPA)-2 system that has been implicated in refractoriness to HLA-matched platelet transfusion and in neonatal immune thrombocytopenic purpura. STUDY DESIGN AND METHODS: The...

Topics

Alleles
Humans
Italy
Methionine
Platelet Glycoprotein GPIb-IX Complex
Threonine
von Willebrand Factor

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