Article
Systematic screening for genetic polymorphism in human platelet glycoprotein Ibalpha.
Immunogenetics - 1 Jan 1996
Kaski S, Kekomäki R, Partanen J
Abstract excerpt
Glycoprotein Ibalpha (GP Ibalpha; CD 42b; hereafter GPIBA) is a component of the cell surface receptor for the von Willebrand factor (vWf) on platelets. Immunizations against various platelet surface antigens play a major role in neonatal alloimmune thrombocytopenia and in post-transfusion purpura. Only one antigenic polymorphism in GPIBA has thus far been established: the HPA-2 (Ko) alloantigen system. To screen...
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