Article
Platelet glycoprotein Ib polymorphism in the Italian population.
Haematologica - 1 Jan 2000
Marchese P, Perutelli P, Caprino D, Mori P G
Abstract excerpt
The glycoprotein Ib (GP Ib) is the major sialoglycoprotein on the platelet membrane and plays an important role in primary hemostasis. It was demonstrated that GP Ib is polymorphic: four different species of GP Ib (designated A, B, C and D) were observed, having molecular weights of 168, 162, 159 and 153 kiloDaltons, respectively. The polymorphism was first studied in the Japanese population and, subsequently, in...
Topics
- Alleles
- Gene Frequency
- Humans
- Italy
- Phenotype
- Platelet Membrane Glycoproteins
- Polymorphism, Genetic
- Receptors, Cell Surface
- Receptors, Thrombin
- United States