Article
Polymorphism of human glycoprotein Ib alpha results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region. Structure/function implications.
The Journal of biological chemistry - 15 May 1992
López J A, Ludwig E H, McCarthy B J
Abstract excerpt
Four polymorphic variants of the platelet receptor for von Willebrand factor, glycoprotein Ib, have been described that differ in molecular weight on sodium dodecyl sulfate-polyacrylamide gels (Moroi, M., Jung, S. M., and Yoshida, N. (1984) Blood 64, 622-629). A recent report localized the polymo...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Western
- DNA
- Ethnicity
- Genetic Variation
- Genotype
- Glycopeptides
- Haplotypes
- Humans
- Leukocytes
- Molecular Sequence Data
- Mucins
- Oligodeoxyribonucleotides
- Platelet Membrane Glycoproteins
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Racial Groups