Article
A novel isoform of platelet glycoprotein Ib alpha is prevalent in African Americans.
American journal of hematology - 1 Jan 1999
Aramaki K M, Reiner A P
Abstract excerpt
The heavy chain of platelet glycoprotein Ib (GPIb) contains two prevalent sequence polymorphisms. The first, Thr/Met145 is responsible for the human platelet alloantigen system, human platelet antigen (HPA)-2. The second is a tandem repeat polymorphism that consists of four variants, A, B, C, and D. Previous linkage studies in Caucasian and Eastern Asian populations have demonstrated that HPA-2a (Thr145) is...
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