Article
The variable number of tandem repeat polymorphism of platelet glycoprotein Ibalpha and risk of coronary heart disease.
Blood - 1 Feb 2004
Afshar-Kharghan Vahid, Matijevic-Aleksic Nevenka, Ahn Chul, Boerwinkle Eric, Wu Kenneth K, López José A
Abstract excerpt
Glycoprotein (GP) Ib-IX-V complex plays an important role in formation of platelet-fibrin clot at the area of damaged vessel wall. One polymorphism of GP Ibalpha, the main component of GP Ib-IX-V complex, is due to variable numbers of tandem repeats (VNTRs) in the macroglycopeptide region of this molecule. We studied the association between the presence of different VNTR alleles of GP Ibalpha and the frequency of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
