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Article

Messenger RNA reprogramming by spliceosome-mediated RNA trans-splicing.

The Journal of clinical investigation - 1 Aug 2003

Garcia-Blanco Mariano A

Abstract excerpt

In the human genome, the majority of protein-encoding genes are interrupted by introns, which are removed from primary transcripts by a macromolecular enzyme known as the spliceosome. Spliceosomes can constitutively remove all the introns in a primary transcript to yield a fully spliced mRNA or a...

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Identifiers

PMID: 12925685
DOI: 10.1172/JCI19462
PMCID: PMC171395

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12925685-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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