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Article

Subdivision of large introns in Drosophila by recursive splicing at nonexonic elements.

Genetics - 1 Jun 2005

Burnette James M, Miyamoto-Sato Etsuko, Schaub Marc A, Conklin Jamie, Lopez A Javier

Abstract excerpt

Many genes with important roles in development and disease contain exceptionally long introns, but special mechanisms for their expression have not been investigated. We present bioinformatic, phylogenetic, and experimental evidence in Drosophila for a mechanism that subdivides many large introns by recursive splicing at nonexonic elements and alternative exons. Recursive splice sites predicted with highly...

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Identifiers

PMID: 15802507
DOI: 10.1534/genetics.104.039701
PMCID: PMC1450422

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