Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant pre-mRNA maturation is caused by LINE insertions into introns of the white gene of Drosophila melanogaster.

Nucleic acids research - 25 Oct 1995

Lajoinie O, Drake M E, Dastugue B, Vaury C

Abstract excerpt

Insertional mutagenesis screens have provided thousands of mutant alleles for analysing genes of varied functions in Drosophila melanogaster. We here document mechanisms of insertional mutagenesis by a LINE element, the I factor, by determining the molecular structure of RNAs produced from two alleles of the white gene of D.melanogaster, wIR1 and wIR6. These alleles result from insertion of the I factor into...

Topics

ATP-Binding Cassette Transporters
Alleles
Amino Acid Sequence
Animals
Base Sequence
DNA Transposable Elements
Drosophila Proteins
Drosophila melanogaster
Eye Proteins
Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Insect

Insect Hormones

Introns

Molecular Sequence Data

Mutagenesis, Insertional

Organ Specificity

RNA Precursors

RNA Splicing

Source

Open in PubMed Open full text

Identifiers

PMID: 7479058
DOI: 10.1093/nar/23.20.4015
PMCID: PMC307336

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7479058-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant pre-mRNA maturation is caused by LINE insertions into introns of the white gene of Drosophila melanogaster.PMID 7479058Read ↗

Functional organization of the white gene enhancer in Drosophila melanogaster.Semantic proximity Read ↗

FB elements can promote exon shuffling: a promoter-less white allele can be reactivated by FB mediated transposition in Drosophila melanogaster.Semantic proximity Read ↗

The Lighten up (Lip) gene of Drosophila melanogaster, a modifier of retroelement expression, position effect variegation and white locus insertion alleles.Semantic proximity Read ↗

Aberrant splicing and transcription termination caused by P element insertion into the intron of a Drosophila gene.Semantic proximity Read ↗

Species-specific signals for the splicing of a short Drosophila intron in vitro.Semantic proximity Read ↗

Generation of alternative Ultrabithorax isoforms and stepwise removal of a large intron by resplicing at exon-exon junctions.Semantic proximity Read ↗

Characterization of enhancer-of-white-apricot in Drosophila melanogaster.Semantic proximity Read ↗

I transposable elements and I-R hybrid dysgenesis in Drosophila.Semantic proximity Read ↗

Genetic enhancement of RNA-processing defects by a dominant mutation in B52, the Drosophila gene for an SR protein splicing factor.Semantic proximity Read ↗

Dosage compensation of the Drosophila white gene requires both the X chromosome environment and multiple intragenic elements.Semantic proximity Read ↗

Weakener of white (Wow), a gene that modifies the expression of the white eye color locus and that suppresses position effect variegation in Drosophila melanogaster.Semantic proximity Read ↗

Unusual misregulation of RNA splicing caused by insertion of a transposable element into the T (Brachyury) locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.