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Article

Aberrant pre-mRNA maturation is caused by LINE insertions into introns of the white gene of Drosophila melanogaster.

Nucleic acids research - 25 Oct 1995

Lajoinie O, Drake M E, Dastugue B, Vaury C

Abstract excerpt

Insertional mutagenesis screens have provided thousands of mutant alleles for analysing genes of varied functions in Drosophila melanogaster. We here document mechanisms of insertional mutagenesis by a LINE element, the I factor, by determining the molecular structure of RNAs produced from two alleles of the white gene of D.melanogaster, wIR1 and wIR6. These alleles result from insertion of the I factor into...

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Identifiers

PMID: 7479058
DOI: 10.1093/nar/23.20.4015
PMCID: PMC307336

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