Article
HPA-1 and HPA-3 polymorphisms of the platelet fibrinogen receptor and coronary artery disease and myocardial infarction.
Thrombosis and haemostasis - 1 Apr 2000
Böttiger C, Kastrati A, Koch W, Mehilli J, Seidl H, Schömig K, von Beckerath N, Schömig A
Abstract excerpt
Platelet fibrinogen receptor (glycoprotein [GP] IIb/IIIa) plays a fundamental role in atherothrombosis. The human platelet antigen (HPA) -1 and the HPA-3 are the most extensively studied polymorphisms of GPIIIa and GPIIb, respectively. This study was designed to test, in a large population, the hypothesis that these polymorphisms represent a risk factor for the occurrence of coronary artery disease (CAD) and...
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