Article
Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: implicated mechanisms for caspase activation.
Proceedings of the National Academy of Sciences of the United States of America - 5 Jan 1999
Kanuka H, Hisahara S, Sawamoto K, Shoji S, Okano H, Miura M
Abstract excerpt
CED-4 protein plays an important role in the induction of programmed cell death in Caenorhabditis elegans through the activation of caspases. However, the precise mechanisms by which it activates caspases remain unknown. To investigate the conservation of CED-4 function in evolution, transgenic D...
Topics
- Adenosine Triphosphate
- Animals
- Animals, Genetically Modified
- Apoptosis
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Calcium-Binding Proteins
- Caspases
- Drosophila
- Drosophila Proteins
- Enzyme Activation
- Evolution, Molecular
- Eye
- Genes, Reporter