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Article

Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair.

Genetics - 1 Apr 2004

Schürer K Anke, Rudolph Christian, Ulrich Helle D, Kramer Wilfried

Abstract excerpt

The MPH1 gene from Saccharomyces cerevisiae, encoding a member of the DEAH family of proteins, had been identified by virtue of the spontaneous mutator phenotype of respective deletion mutants. Genetic analysis suggested that MPH1 functions in a previously uncharacterized DNA repair pathway that protects the cells from damage-induced mutations. We have now analyzed genetic interactions of mph1 with a variety of...

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Identifiers

PMID: 15126389
DOI: 10.1534/genetics.166.4.1673
PMCID: PMC1470801

Genes

REV1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair.PMID 15126389Read ↗

MPH1, a yeast gene encoding a DEAH protein, plays a role in protection of the genome from spontaneous and chemically induced damage.Semantic proximity Read ↗

Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3' to 5' DNA helicase.Semantic proximity Read ↗

Budding yeast Mph1 promotes sister chromatid interactions by a mechanism involving strand invasion.Semantic proximity Read ↗

Genetic evidence for a role of Saccharomyces cerevisiae Mph1 in recombinational DNA repair under replicative stress.Semantic proximity Read ↗

Genetic interactions between error-prone and error-free postreplication repair pathways in Saccharomyces cerevisiae.Semantic proximity Read ↗

HIM1, a new yeast Saccharomyces cerevisiae gene playing a role in control of spontaneous and induced mutagenesis.Semantic proximity Read ↗

Mph1p promotes gross chromosomal rearrangement through partial inhibition of homologous recombination.Semantic proximity Read ↗

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Mph1 requires mismatch repair-independent and -dependent functions of MutSalpha to regulate crossover formation during homologous recombination repair.Semantic proximity Read ↗

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