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Article

Restoration of the mucous phenotype by retinoic acid in retinoid-deficient human bronchial cell cultures: changes in mucin gene expression.

American journal of respiratory cell and molecular biology - 1 Jan 1999

Koo J S, Yoon J H, Gray T, Norford D, Jetten A M, Nettesheim P

Abstract excerpt

Retinoid-deficient cultures of airway epithelial cells undergo squamous differentiation. Treatment of such cultures with retinoic acid (RA) leads to restoration of the mucous phenotype. The purpose of our study was to characterize the cellular and molecular changes following RA treatment of retinoid-deficient human tracheobronchial epithelial cell cultures. Of particular interest was to determine when during the...

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Identifiers

PMID: 9870916
DOI: 10.1165/ajrcmb.20.1.3310

Genes

MUC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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