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Mucin Gene Expression during Differentiation of Human Airway Epithelia <i>In Vitro</i> : MUC4 and MUC5B Are Strongly Induced

1 Apr 1999

Abstract excerpt

Mucus hypersecretion is characteristic of chronic airway diseases. However, regulatory mechanisms are poorly understood. Human airway epithelial cells grown on permeable supports at the air-liquid interface (ALI) develop a mucociliary morphology resembling that found in vivo. Such cultures provide a model for studying secretory cell lineage, differentiation, and function, and may provide insight regarding events...

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Identifiers

PMID: 10100990
DOI: 10.1165/ajrcmb.20.4.3442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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