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Article

Mechanisms involved in graft-versus-host disease induced by the disparity of minor histocompatibility M1s antigens.

Scandinavian journal of immunology - 1 Mar 1999

Kawamura T, Kawachi Y, Kuwano Y, Sugahara S, Weerasinghe A, Kosaka T, Seki S, Abo T

Abstract excerpt

In this study we investigated which type of T cells: high T-cell receptor (TCRhigh, cells of thymic origin) or intermediate TCR (TCRint, cells of extrathymic origin), expanded in the liver and other organs, resulting in the induction of graft-versus-host disease (GVHD) with minor lymphocyte stimulating (M1s) disparity. When 6.5 Gy-irradiated BALB/c (H-2d M1s-1b2a) mice were injected with interleukin-2 receptor...

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Identifiers

PMID: 10102643
DOI: 10.1046/j.1365-3083.1999.00497.x

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