Article
The inheritance of glomerulosclerosis in mice is controlled by multiple quantitative trait loci.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Dec 1998
Lenz O, Zheng F, Vilar J, Doublier S, Lupia E, Schwedler S, Striker L J, Striker G E
Abstract excerpt
BACKGROUND: Glomerulosclerosis, the common terminal event in chronic glomerular diseases such as diabetic nephropathy or IgA nephropathy, leads to end-stage renal disease. The considerable variation in both the risk of developing glomerulosclerosis and the rate of progression in individual patients suggest a role for genetic factors which have not been identified so far. In this study we sought to examine the...
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