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Article

Renal phenotype is exacerbated in Os and lpr double mutant mice.

Kidney international - 1 Sept 2004

Jarad George, Lakhe-Reddy Sujata, Blatnik Jeffrey, Koepke Morgan, Khan Shenaz, El-Meanawy M Ashraf, O'Connor Andrew S, Sedor John R, Schelling Jeffrey R

Abstract excerpt

BACKGROUND: ROP-Os/+ mice are born with oligosyndactyly and oligonephronia and develop renal dysfunction, which includes renal tubular epithelial cell (RTC) Fas-dependent apoptosis and tubular atrophy. MRL/lpr mice harbor a Fas-inactivating mutation and develop glomerulonephritis, whereas mice ex...

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PMID: 15327396
DOI: 10.1111/j.1523-1755.2004.00851.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15327396-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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