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Article

TP53 mutations in endometrial cancers: relation to PTEN gene defects.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Feb 2010

Janiec-Jankowska Aneta, Konopka Bozena, Goluda Cyprian, Najmoła Urszula

Abstract excerpt

OBJECTIVE: The PTEN and TP53 genes participate in the carcinogenesis of many malignancies, but the role of both genes in endometrial carcinogenesis is not fully elucidated. The aim of the study was to determine the quality and the frequency of incidence of TP53 and PTEN gene mutations and to asse...

Read the complete abstract on PubMed

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Share to Aged, 80 and over
Share to Carcinoma, Endometrioid
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endometrial Neoplasms

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Share to Genes, p53

Share to Polymorphism, Single-Stranded Conformational

Share to PTEN Phosphohydrolase

Source

Identifiers

PMID: 20169661
DOI: 10.1111/igc.0b013e3181c83675

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20169661-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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