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Article

[High molecular weight kininogen in inflammation and angiogenesis: a review of its properties and therapeutic applications].

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion - 1 Jan 2000

Isordia-Salas Irma, Sainz Irma M, Pixley Robin A, Martínez-Murillo Carlos, Colman Robert W

Abstract excerpt

The plasma kallikrein-kinin system (KKS) participates in the pathogenesis of inflammatory reactions involved in cellular injury, coagulation, fibrinolysis, kinin formation, complement activation, cytokine secretion and release of proteases. It has been shown that KKS activation in the systemic inflammatory response syndrome results in decrease of its component plasma proteins. Similar changes have been documented...

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PMID: 16708906

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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