Article
Mechanisms regulating the expression, self-maintenance, and signaling-function of the bradykinin B2 and B1 receptors.
Journal of cellular physiology - 1 Dec 2002
Prado Gregory N, Taylor Linda, Zhou Xiaofeng, Ricupero Dennis, Mierke Dale F, Polgar Peter
Abstract excerpt
Bradykinin (BK) is a potent short-lived effector belonging to a class of peptides known as kinins. It participates in inflammatory and vascular regulation and processes including angioedema, tissue permeability, vascular dilation, and smooth muscle contraction. BK exerts its biological effects through the activation of the bradykinin B2 receptor (BKB2R) which is G-protein-coupled and is generally constitutively...
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