Effects of murine recombinant interleukin-10 on the inflammatory disease of rats transgenic for HLA-B27 and human beta 2-microglobulin.

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Article

Effects of murine recombinant interleukin-10 on the inflammatory disease of rats transgenic for HLA-B27 and human beta 2-microglobulin.

European cytokine network - 1 Jun 1998

Bertrand V, Quéré S, Guimbaud R, Sogni P, Chauvelot-Moachon L, Tulliez M, Lamarque D, Charreire J, Giroud J P, Couturier D, Chaussade S, Breban M

Abstract excerpt

Rats transgenic for HLA-B27 and human beta 2-microglobulin develop a spontaneous, multisystem, inflammatory disease that resembles human B27-associated disease and that involves the gut mucosa. This model predominantly affects the colon and is characterized by an extensive infiltration of the muc...

Topics

Animals
Animals, Genetically Modified
Colitis
Female
HLA-B27 Antigen
Humans
Inflammatory Bowel Diseases
Interleukin-10
Lymph Nodes
Mice
Nitric Oxide Synthase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nitric Oxide Synthase Type II

Organ Size

Peroxidase

Phenotype

RNA, Messenger

Rats

Rats, Inbred F344

Source

Open in PubMed

Identifiers

PMID: 9681392

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9681392-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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