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Article

Chromosome 7 rearrangements in glioblastomas; loci adjacent to EGFR are independently amplified.

Journal of neuropathology and experimental neurology - 1 Dec 1998

Liu L, Ichimura K, Pettersson E H, Collins V P

Abstract excerpt

The first gene found to be amplified in human glioblastomas was EGFR at 7p12. More recently the MET gene at 7q31 was also reported amplified. We have studied chromosome 7 in a series of 47 glioblastomas by FISH, RFLP and microsatellite analysis. Four per cent (2/47) had 1 centromere, 26% (12/47) 2, 32% (15/47) 3, 4% (2/47) 4, and 34% (16/47) had subpopulations with variable numbers of chromosome 7 centromeres. In...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

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Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 9862636
DOI: 10.1097/00005072-199812000-00005

Genes

EGFR
MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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