pH-dependent growth retardation of Escherichia coli caused by overproduction of Na+/H+ antiporter.

doi:10.1248/bpb.21.1128

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Article

pH-dependent growth retardation of Escherichia coli caused by overproduction of Na+/H+ antiporter.

Biological & pharmaceutical bulletin - 1 Nov 1998

Inoue H, Noumi T, Shimomura T, Takimoto N, Tsuchiya T, Kanazawa H

Abstract excerpt

The overproduction of Na+/H+ antiporter NhaA in Escherichia coli caused growth retardation. Quantities and the activity of the antiporter were studied for their causative roles in terms of this retardation. We constructed a series of nhaA-expression plasmids differing in their transcriptional and...

Topics

Cell Division
Escherichia coli
Gene Expression Regulation, Bacterial
Genetic Complementation Test
Hydrogen-Ion Concentration
Mutation
Plasmids
Sodium-Hydrogen Exchangers
Transformation, Bacterial

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