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Article

Interstitial loss and gain of sequences on chromosome 22 in meningiomas with normal karyotype.

International journal of oncology - 1 Feb 2005

Prowald Alexandra, Wemmert Silke, Biehl Claudia, Storck Simone, Martin Thomas, Henn Wolfram, Ketter Ralf, Meese Eckart, Zang Klaus D, Steudel Wolf-Ingo, Urbschat Steffi

Abstract excerpt

In nearly half of sporadic low grade meningiomas no chromosome aberration can be detected. In the majority of the other half chromosome 22 is lost. In higher grade meningiomas this loss is followed by characteristic secondary chromosome aberrations. Regarding the molecular findings in Schwannomas, homozygous loss or mutation of the NF2 gene located on chromosome 22, was supposed also to be the primary event in...

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PMID: 15645123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interstitial loss and gain of sequences on chromosome 22 in meningiomas with normal karyotype.PMID 15645123Read ↗

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