Article
Deficiency of intercellular adhesion molecule 1 attenuates microcirculatory disturbance and infarction size in focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Dec 1998
Kitagawa K, Matsumoto M, Mabuchi T, Yagita Y, Ohtsuki T, Hori M, Yanagihara T
Abstract excerpt
Recent evidence has shown crucial roles for cell-adhesion molecules in inflammation-induced rolling, adhesion, and accumulation of neutrophils in tissue. Intercellular adhesion molecule-1 (ICAM-1) is one of these adhesion molecules. Previous studies have shown marked reduction in the size of infa...
Topics
- Animals
- Brain
- Brain Ischemia
- Cerebral Infarction
- Cerebrovascular Circulation
- Collateral Circulation
- Genotype
- Intercellular Adhesion Molecule-1
- Ischemic Attack, Transient
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Microcirculation
