Microsatellite instability and frameshift mutations in the Bax gene in hereditary nonpolyposis colorectal carcinoma.

doi:10.1111/j.1349-7006.1998.tb00491.x

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Article

Microsatellite instability and frameshift mutations in the Bax gene in hereditary nonpolyposis colorectal carcinoma.

Japanese journal of cancer research : Gann - 1 Oct 1998

Sakao Y, Noro M, Sekine S, Nozue M, Hirohashi S, Itoh T, Noguchi M

Abstract excerpt

We studied microsatellite instability (MI) and bax gene abnormalities in colorectal carcinomas from 36 patients diagnosed as having hereditary nonpolyposis colorectal cancers (HNPCC) according to the clinical criteria (12 with confirmed HNPCC in group A and 24 at high risk of HNPCC in group B) an...

Topics

Colorectal Neoplasms
Colorectal Neoplasms, Hereditary Nonpolyposis
Dinucleotide Repeats
Frameshift Mutation
Genetic Markers
Humans
Microsatellite Repeats
Phenotype
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcl-2
Proto-Oncogenes
Risk Factors

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Identifiers

PMID: 9849580
DOI: 10.1111/j.1349-7006.1998.tb00491.x
PMCID: PMC5921699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9849580-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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bcl-2-Associated X Protein