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Article

Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype.

Cancer research - 1 Oct 1997

Yamamoto H, Sawai H, Perucho M

Abstract excerpt

An exacerbated genomic instability characterizes hereditary and sporadic gastrointestinal cancer of the microsatellite mutator phenotype (MMP), generating somatic frameshift mutations in genes containing mononucleotide repeats. We have recently shown that approximately 50, 40, and 30% of MMP+ colon tumors harbor frameshift mutations in (G)8, (A)8, and (C)8 tracks within the proapoptotic gene BAX and the hMSH3 and...

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Source

Identifiers

PMID: 9331106

Genes

BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype.PMID 9331106Read ↗

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