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Article

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

Science (New York, N.Y.) - 14 Feb 1997

Rampino N, Yamamoto H, Ionov Y, Li Y, Sawai H, Reed J C, Perucho M

Abstract excerpt

Cancers of the microsatellite mutator phenotype (MMP) show exaggerated genomic instability at simple repeat sequences. More than 50 percent (21 out of 41) of human MMP+ colon adenocarcinomas examined were found to have frameshift mutations in a tract of eight deoxyguanosines [(G)8] within BAX, a...

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Identifiers

PMID: 9020077
DOI: 10.1126/science.275.5302.967

Genes

BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9020077-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.PMID 9020077Read ↗

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