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Article

tRNA(2Gln) mutants that translate the CGA arginine codon as glutamine in Escherichia coli.

RNA (New York, N.Y.) - 1 Dec 1998

Tsai F, Curran J F

Abstract excerpt

We present a novel missense suppression system for the selection of tRNA(2GIn) mutants that can efficiently translate the CGA (arginine) codon as glutamine. tRNA(2Gln) mutants were cloned from a partially randomized synthetic gene pool using a plasmid vector that simultaneously expresses the tRNA gene and, to ensure efficient aminoacylation, the glutamine aminoacyl-tRNA synthetase gene (glnS). tRNA mutants that...

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Source

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Identifiers

PMID: 9848650
DOI: 10.1017/s1355838298981274
PMCID: PMC1369722

Genes

CGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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