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Article

Mutant enzymes and tRNAs as probes of the glutaminyl-tRNA synthetase: tRNA(Gln) interaction.

Biochimie - 1 Dec 1991

Englisch-Peters S, Conley J, Plumbridge J, Leptak C, Söll D, Rogers M J

Abstract excerpt

This paper focuses on several aspects of the specificity of mutants of Escherichia coli glutaminyl-tRNA synthetase (GlnRS) and tRNA(Gln). Temperature-sensitive mutants located in glnS, the gene for GlnRS, have been described previously. The mutations responsible for the temperature-sensitive phenotype were analyzed, and pseudorevertants of these mutants isolated and characterized. The nature of these mutations is...

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PMID: 1725262
DOI: 10.1016/0300-9084(91)90184-3

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