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Article

Selectivity and specificity in the recognition of tRNA by E coli glutaminyl-tRNA synthetase.

Biochimie - 1 Jan 1993

Rogers M J, Weygand-Durasević I, Schwob E, Sherman J M, Rogers K C, Adachi T, Inokuchi H, Söll D

Abstract excerpt

The specific recognition by Escherichia coli glutaminyl-tRNA synthetase (GlnRS) of tRNA(Gln) is mediated by extensive protein:RNA contacts and changes in the conformation of tRNA(Gln) when complexed with GlnRS. In vivo accuracy of aminoacylation depends on two factors: competition between synthetases, and the context and recognition of identity elements in the tRNA. The structure of the tRNA(Gln):GlnRS complex...

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PMID: 8199243
DOI: 10.1016/0300-9084(93)90007-f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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