Article
Selectivity and specificity in the recognition of tRNA by E coli glutaminyl-tRNA synthetase.
Biochimie - 1 Jan 1993
Rogers M J, Weygand-Durasević I, Schwob E, Sherman J M, Rogers K C, Adachi T, Inokuchi H, Söll D
Abstract excerpt
The specific recognition by Escherichia coli glutaminyl-tRNA synthetase (GlnRS) of tRNA(Gln) is mediated by extensive protein:RNA contacts and changes in the conformation of tRNA(Gln) when complexed with GlnRS. In vivo accuracy of aminoacylation depends on two factors: competition between synthet...
Topics
- Amino Acyl-tRNA Synthetases
- Anticodon
- Base Sequence
- Escherichia coli
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Protein Conformation
- RNA, Transfer, Gln
- Substrate Specificity