Article
Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.
Journal of molecular biology - 2 Jun 2000
Sherlin L D, Bullock T L, Newberry K J, Lipman R S, Hou Y M, Beijer B, Sproat B S, Perona J J
Abstract excerpt
The position of the tertiary Levitt pair between nucleotides 15 and 48 in the transfer RNA core region suggests a key role in stabilizing the joining of the two helical domains, and in maintaining the relative orientations of the D and variable loops. E. coli tRNA(Gln) possesses the canonical Pu15-Py48 trans pairing at this position (G15-C48), while the tRNA(Cys) species from this organism instead features an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
