Article
No association between the serotonin transporter-linked promoter region polymorphism and either schizophrenia or density of the serotonin transporter in human hippocampus.
Molecular medicine (Cambridge, Mass.) - 1 Oct 1998
Naylor L, Dean B, Pereira A, Mackinnon A, Kouzmenko A, Copolov D
Abstract excerpt
BACKGROUND: Allelic association case-control analysis of a deletion/insertion polymorphism in the serotonin transporter-linked polymorphic region (5-HTTLPR) has suggested associations with unipolar disorder, bipolar disorder, depression, and Alzheimer's disease. Moreover, the heterozygous long fo...
Topics
- Carrier Proteins
- Case-Control Studies
- Genotype
- Hippocampus
- Humans
- Membrane Glycoproteins
- Membrane Transport Proteins
- Nerve Tissue Proteins
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Schizophrenia
- Serotonin Plasma Membrane Transport Proteins