Article
Susceptibility for schizophrenia is not influenced by a functional insertion/deletion variant in the promoter of the serotonin transporter gene.
European archives of psychiatry and clinical neuroscience - 1 Jan 1998
Stöber G, Jatzke S, Heils A, Jungkunz G, Fuchs E, Knapp M, Riederer P, Lesch K P
Abstract excerpt
A possible dysregulation of serotonergic neurotransmission has been implicated in the aetiology of schizophrenic psychoses. In the present study we analysed allelic and genotypic variations of a recently described functional polymorphic region in the promoter of the human serotonin transporter gene (5-HTTLPR) and a variable tandem repeat (VNTR) in intron 2 of the 5-HTT gene. We investigated 413 unrelated...
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